Isolation and identification of endophytic fungi from \(\textit{Catharanthus roseus}\) and \(\textit{Scutallaria barbata}\)

Endophytic fungi, microfungi that internally infect living plant tissues, are reported to have the ability synthesize many enzymes, growth hormones and pharmaceutically active compounds similar those in their hosted plants. This has opened a potential path of using endophytic fungi as bioreactor for mass production bioactive at lower cost. Therefore, it is necessary establish robust procedure isolation identification fungal strains capable producing desired biological compounds. In this study, we an effective surface sterilization 3 types tissue samples (root, shoot leaf) 2 herbaceous plants (Catharanthus roseus Scutallaria barbata) commercial bleach (5% NaOCl), from sterilized isolated by ITS sequencing analysis. A total 48 were successfully collected Dan Phuong (Ha Noi), Phu Dien Noi) Hai Duong city (Hai Duong). Based on results morphological observation analysis, classified one four species, including Clasdosporium colombiae, Cladosporium halotolerans, Corynespora cassiicola Albifimbria terrestris. The species pharmacologically will be investigated future studies.